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Decreased fat mass in HFD-fed mice after treatment with D-4F. Eight-week-old C57BL/6J male mice were fed with HFD for 12 weeks, and then injected with either D-4F (n= 6) or PBS (n= 5) continuously for 4 weeks. The body weight (A), food intake (B), percentage of body fat content (C) and the weight of epididymal and retroperitoneal fat pads (D) were measured. The data are shown in mean ± S.D. * indicates P < 0.05 by Student’s t-test between the two groups.
