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Elevated energy expenditure in D-4F-treated DIO mice. Respiratory exchange ratio (A) and metabolic rates (B) were measured in D-4F- or PBS-injected mice (n= 6 for D-4F group mice and n= 5 for the control group). The data are shown in mean ± S.D. * indicates P < 0.05 and ∧ indicates P < 0.01 by Student’s t-test between the two groups.
