Table 1.
Serum parameters in ApoA-I-Tg and D-4F-treated mice after HFD feeding
| TCHO (mM) | TG (mM) | HDL-C (mM) | LDL-C (mM) | FFA (mM) | Glucose (mM) | Insulin (μIU/ml) | |
|---|---|---|---|---|---|---|---|
| Wild-type (n= 6) | 4.46(0.50) | 0.76(0.20) | 2.85(0.32) | 0.96(0.25) | 1.15(0.15) | 10.25(1.30) | 10.36(1.56) |
| ApoA-I Tg (n= 6) | 8.36(2.31)** | 0.75(0.26) | 5.31(1.04)** | 2.04(1.39) | 0.79(0.13)** | 9.20(1.62) | 10.23(2.49) |
| Control (n= 5) | 5.73(0.38) | 0.54(0.18) | 3.27(0.18) | 1.66(0.25) | 0.63(0.15) | 9.54(0.97) | 8.74(1.22) |
| D-4F (n= 6) | 5.62(0.94) | 0.59(0.20) | 3.27(0.43) | 1.64(0.49) | 0.61(0.07) | 10.08(1.64) | 11.22(3.37) |
All parameters were measured in mice fasted overnight except for blood glucose that was examined after fasting for 3 hrs. The data are shown as mean (S.D.). ‘n’ indicates the number of mouse used in each group. ** indicates P < 0.01 as a comparison between the ApoA-I-Tg mice and the wild-type mice.