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. 2014 Feb 12;9(2):e87861. doi: 10.1371/journal.pone.0087861

Table 2. Demographic, reproductive and lifestyle characteristics of participants by equol and O-DMA phenotypes.

Non-Equol producers equol producers P Non-O-DMA producers O-DMA producers P
Demographic and reproductive characteristics
n 292 305 256 341
Age (y) 57.6±4.6 57.9±4.8 0.527 58.1±5.0 57.6±4.5 0.208
Menopausal years (y) 8.2±5.3 8.8±5.9 0.217 8.8±6.2 8.4±5.3 0.365
Age at menarche(y) 13.2±1.8 13.0±1.8 0.380 13.3±1.8 13.0±1.8 0.090
Ever use of contraceptives(%) 126 (50.6) 154 (46.7) 0.191 98 (45.2) 182 (50.3) 0.264
Ever use of HRT (%) 38 (15.3) 51 (15.5) 0.522 36 (16.6) 53 (14.6) 0.303
Dietary intake (from FFQ)
n 244 329 213 360
Energy (kcal/d) 2100.7±1018.6* 1958.0±912.2 0.044 2031.7±1013.6 2011.2±929.4 0.805
Protein (g/1000 kcal) 55.8±13.2 54.9±13.5 0.419 54.5±13.5 55.8±13.3 0.274
Total fat (g/1000 kcal) 21.2±6.9 20.9±6.8 0.612 21.1±6.5 20.9±7.0 0.752
Carbohydrate (g/1000 kcal) 166.3±17.0 167.0±17.6 0.598 166.5±16.0 166.8±18.1 0.865
Fiber (g/1000 kcal) 21.0±8.8 20.4±8.3 0.389 20.2±8.2 20.9±8.6 0.292
Cholesterol (mg/1000 kcal) 146.2±90.1 146.9±77.4 0.292 143.8±78.4 148.3±85.7 0.538
Isoflavones (mg/1000 kcal) # 7.03±7.83 6.12±6.84 0.145 7.05±8.44 6.37±6.19 0.263
Other lifestyle factors
N 292 305 256 341
Total PA (MET-min/d) 1445.6±728.2 1413.0±816.1 0.620 1460.4±808.8 1407.0±761.0 0.427
 Occupational PA 586.1±759.5 474.4±741.1 0.077 502.2±731.8 534.8±762.2 0.615
 Housework PA 558.7±459.9 549.8±489.5 0.823 555.9±446.6 552.2±494.3 0.929
 Sports PA 141.0±166.2* 219.0±254.8 0.000 169.9±192.3* 211.4±267.9 0.031
Sitting hours (h/d) 3.3±1.9 3.3±2.1 0.981 3.2±2.1 3.4±2.0 0.273
Regular tea drinking(%) 195 (78.6) 268 (81.7) 0.397 176 (82.2) 287 (79.3) 0.447
Regular alcohol drinking(%) 18 (7.3) 30 (9.1) 0.256 19 (8.8) 29 (8.0) 0.757
Regular coffee drinking(%) 84 (33.9) 127 (38.7) 0.256 78 (36.4) 133 (36.7) 0.944
Smoking (%) 1 (0.4) 2 (0.6) 0.672 1 (0.5) 2 (0.6) 0.693
Passive smoking (%) 43 (17.4) 48 (14.6) 0.211 37 (15.3) 54 (15.0) 0.481

Data are presented as mean ± standard deviation for continuous variables or number (%) for categorical variables. T-test was applied for continuous variables and Chi-square test for categorical variables. HRT indicates hormone replacement treatment; FFQ indicates food frequency questionnaires; PA indicates physical activity; Regular drinking means drinking alcohol, tea or coffee more than 1 time per week; METs are multiples of resting metabolic rates and a MET-minute is computed by multiplying the MET score of an activity by the minutes performed. Dietary nutrients intakes were calculated mainly based on the China Food Composition Table 2002 and 2004.

#

denotes testing by non-parametric Mann-Whitney Test due to data heterogeneity;

*denotes significant difference between producers and non-producers by t-test (P<0.05).