Table 5.
Factors associated with early initiation of primary PCP prophylaxis from 1998-2009
| |
Univariate models |
Multivariate model* |
||||
|---|---|---|---|---|---|---|
| Initiators (N = 156) N (%) or median (IQR) | Delayers (N = 252) N (%) or median (IQR) | OR (95% CI) | p | OR (95% CI) | P | |
|
Demographics | ||||||
| Gender (% Male) |
144 (92%) |
227 (90%) |
1.32 (0.64 - 2.71) |
0.45 |
1.00 (0.33 - 3.03) |
>0.99 |
| Age |
36.9 (29.2 - 43.0) |
37.4 (32.2 - 42.5) |
0.99 (0.97 - 1.01) |
0.36 |
0.98 (0.95 - 1.01) |
0.27 |
| Race/ethnicity | ||||||
| Caucasian |
61 (39%) |
100 (40%) |
Referent |
|
Referent |
|
| African American |
72 (46%) |
122 (48%) |
0.97 (0.63 - 1.49) |
0.88 |
1.21 (0.71 - 2.09) |
0.48 |
| Hispanic/Latino/other |
23 (15%) |
30 (12%) |
1.26 (0.67 - 2.36) |
0.48 |
1.35 (0.61 - 3.00) |
0.46 |
| Marital status (% married) |
63 (41%) |
71 (31%) |
1.50 (0.98 - 2.30) |
0.06 |
1.52 (0.89 - 2.59) |
0.12 |
|
Military characteristics | ||||||
| Rank | ||||||
| Officer/warrant |
19 (12%) |
24 (10%) |
1.33 (0.70 - 2.54) |
0.38 |
1.76 (0.74 - 4.15) |
0.20 |
| Enlisted |
121 (78%) |
199 (79%) |
Referent |
|
Referent |
|
| N/A |
16 (10%) |
24 (10%) |
1.12 (0.57 - 2.20) |
0.73 |
1.72 (0.54 - 5.47) |
0.36 |
| Duty status | ||||||
| Active |
82 (53%) |
109 (43%) |
Referent |
|
Referent |
|
| Retired |
63 (40%) |
118 (47%) |
0.71 (0.47 - 1.08) |
0.11 |
1.16 (0.59 - 2.25) |
0.67 |
| Dependent |
11 (7%) |
25 (10%) |
0.58 (0.27 - 1.26) |
0.17 |
0.36 (0.09 - 1.53) |
0.17 |
|
HIV characteristics | ||||||
| Duration of HIV infection (years) |
2.5 (0.1 - 8.8) |
6.6 (1.8 - 10.9) |
0.93 (0.89 - 0.97) |
<0.001 |
0.99 (0.93 - 1.05) |
0.70 |
| Log10 HIV RNA |
4.8 (4.3 - 5.2) |
4.5 (3.6 - 5.0) |
1.49 (1.21 - 1.83) |
<0.001 |
1.25 (0.98 - 1.60) |
0.07 |
| CD4 count* |
130.0 (68.5 - 167.0) |
169.0 (131.5 - 187.0) |
0.59 (0.49 – 0.72) |
<0.001 |
0.55 (0.42 – 0.70) |
<0.001 |
| Prior ART use | ||||||
| None |
92 (59%) |
81 (32%) |
Referent |
|
Referent |
|
| ART |
14 (9%) |
24 (10%) |
0.51 (0.25 - 1.06) |
0.07 |
0.81 (0.30 - 2.15) |
0.67 |
| HAART |
50 (32%) |
147 (58%) |
0.30 (0.19 - 0.46) |
<0.001 |
0.48 (0.25 - 0.91) |
0.03 |
| Prior AIDS |
24 (15%) |
36 (14%) |
1.09 (0.62 - 1.91) |
0.76 |
1.00 (0.45 - 2.19) |
>0.99 |
| History of mental health diagnosis | ||||||
| Depression |
19 (12%) |
46 (18%) |
0.63 (0.35 - 1.13) |
0.12 |
0.82 (0.41 - 1.65) |
0.58 |
| Other mental health diagnosis |
13 (8%) |
16 (6%) |
1.24 (0.58 - 2.68) |
0.58 |
1.52 (0.61 - 3.79) |
0.36 |
| None | 124 (79%) | 190 (75%) | Referent | Referent | ||
*Univariate and Multivariate models are per 50 cells/mm3.