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. 2014 Jan 24;33(1):11. doi: 10.1186/1756-9966-33-11

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Copyright © 2014 Zeekpudsa et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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NQO1 over-expression attenuates the p53 pathway in KKU-M214 cells. A-D, Western blots of p53 (A), p21 (B), cyclin D1 (C), and Bax (D) protein in KKU-M214-NQO1 over-expressed cells after treatment with 5-FU 3 μM (48 hr), Doxo 0.1 μM (24 hr), and Gem 0.1 μM (48 hr). The relative bars that were normalized with β-actin of each band are shown below the Western blot images. *p < 0.05 vs the treated control vector transfected cells. **p < 0.05 vs the untreated control vector transfected cells.