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. 2014 Feb 12;9(2):e88337. doi: 10.1371/journal.pone.0088337

Table 2. Details of candidate genes under study and involved in different KEGG immune pathways.

KEGG Path ID KEGG Pathway No. Genes Candidate Genes
bta04630 Jak-STAT signaling pathway 14 CSF2RB,IL10,IL20RA,IL2RA,IL2RB,IL6R,LEPR,PIK3CD,PIK3R3,PRLR,PTPN6,STAT2,STAT3,STAT5B
bta04151 PI3K-Akt signaling pathway 8 IL2RA,IL2RB,IL6R,ITGA5,ITGB7,PIK3CD,PIK3R3,PRLR
bta04060 Cytokine-cytokine receptor interaction 8 CSF2RB,IL10,IL20RA,IL2RA,IL2RB,IL6R,LEPR, PRLR
bta04620 Toll-like receptor signaling pathway 5 PIK3CD,PIK3R3,TLR5,TLR7,TLR8
bta04062 Chemokine signaling pathway 5 PIK3CD,PIK3R3,STAT2,STAT3,STAT5B
bta04660 T cell receptor signaling pathway 4 IL10,PIK3CD,PIK3R3,PTPN6
bta04640 Hematopoietic cell lineage 3 IL2RA,IL6R,ITGA5
bta04650 Natural killer cell mediated cytotoxicity 3 PIK3CD,PIK3R3,PTPN6
bta04662 B cell receptor signaling pathway 3 PIK3CD,PIK3R3,PTPN6
bta04145 Phagosome 2 ITGA5
bta04520 Adherens junction 2 PTPN6,PTPRB
bta04664 Fc epsilon RI signaling pathway 2 PIK3CD,PIK3R3
bta04666 Fc gamma R-mediated phagocytosis 2 PIK3CD,PIK3R3
bta04670 Leukocyte transendothelial migration 2 PIK3CD,PIK3R3
bta04672 Intestinal immune network for IgA production 2 IL10,ITGB7
bta04010 MAPK signaling pathway 1 DDIT3
bta04142 Lysosome 1 SLC11A2
bta04340 Hedgehog signaling pathway 1 GLI1