Table 1.
Preoperative and postoperative characteristics of RRP and LRP patients
| |
Surgical technique |
|
||
|---|---|---|---|---|
| Characteristics | RRP | LRP | Total | p-value* |
| Patients (n) |
168 |
171 |
339 |
|
| Age (yrs) |
|
|
|
0.678 MW |
| Mean ± SD |
62.6 ± 5.4 |
62.3 ± 5.7 |
62.5 ± 5.6 |
|
| Median (Range) |
64 (43–73) |
64 (46–74) |
64 (43–76) |
|
| PSA (ng/ml) |
|
|
|
0.737 MW |
| Mean ± SD |
10.1 ± 11.9 |
9.2 ± 6.9 |
9.7 ± 9.6 |
|
| Median (Range) |
7.4 (0.6-99.0) |
7.2 (0.6-50.6) |
7.4 (0.6-99.0) |
|
| Clinical stage (%) |
|
|
|
0.525 |
| cT1 |
94/121 (77.7) |
120/167 (71.9) |
214/288 (74.3) |
|
| cT2 |
25/121 (20.7) |
43/167 (25.7) |
68/288 (23.6) |
|
| cT3 |
2/121 (1.7) |
4/167 (2.4) |
6/288 (2.1) |
|
| Biopsy Gleason score (%) |
|
|
|
0.328 |
| ≤ 6 |
78/146 (53.4) |
103/167 (61.7) |
181/313 (57.8) |
|
| 7 |
52/146 (35.6) |
50/167 (29.9) |
1102/313 (32.6) |
|
| 8-9 |
16/146 (11.0) |
14/167 (8.4) |
30/313 (9.6) |
|
| Pathology weight (g) |
|
|
|
0.024 MW |
| Mean ± SD |
58 ± 22 |
53 ± 20 |
55 ± 21 |
|
| Median (Range) |
53 (27–150) |
49 (21–173) |
50 (21–173) |
|
| Prostatectomy Gleason score (%) |
|
|
|
0.533 |
| ≤ 6 |
49/161 (30.4) |
43/171 (25.1) |
92/332 (58.6) |
|
| 7 |
91/161 (56.5) |
106/171 (62.0) |
197/332 (59.3) |
|
| 8-9 |
21/161 (13.0) |
22/171 (12.9) |
43/332 (13.0) |
|
| Extraprostatic extension |
45/161 (28.0) |
51/171 (29.8) |
96/332 (28.9) |
0.798 |
| Seminal vesicle invasion |
25/161 (15.5) |
10/171 (5.8) |
35/332 (10.5) |
0.008 |
| Lymph node invasion |
14/156 (9.0) |
3/64 (4.7) |
17/220 (7.7) |
0.422 |
| Positive surgical margin |
35/158 (22.2) |
45/170 (26.5) |
80/328 (24.4) |
0.435 |
| pT2 R1 |
13 (10.5) |
21 (17.5) |
34 (13.9) |
0.006 |
| Nerve sparing (%) |
|
|
|
<0.001 |
| None |
25/168 (14.9) |
92/171 (53.8) |
117/339 (34.5) |
|
| Unilaterally |
3/168 (1.8) |
39/171 (22.8) |
42/339 (12.4) |
|
| Bilaterally |
140/168 (83.3) |
40/171 (23.4) |
180/339 (53.1) |
|
| Time interval to interview (mo) |
|
|
|
0.222 |
| Mean ± SD |
24 ± 16 |
24 ± 12 |
24 ± 14 |
|
| Median (Range) | 17 (9–62) | 22 (9–52) | 19 (9–62) | |
*Indicates test for comparison among the two age cohorts. All tests are chi-squared, unless stated otherwise.
MW: Mann –Whitney-U-Test.
pT2 R1 – organ confined disease with positive surgical margin.