Table 2.
Region of interest (ROI) results of the diagnosis×face emotion×attention state analysis
Area of activation | BA | Side | Cluster size | MNI coordinates x, y, z | F | p FWE corrected | Attention condition, face emotion versus fixation | Between-group differences |
---|---|---|---|---|---|---|---|---|
Amygdala | L | 215 | −22, 0, −18 | 3.58 | 0.006 | Explicit (Hostility) | BD>HC* | |
Fearful | ||||||||
Passive | BD>HC* | |||||||
Anger | ||||||||
Amygdala | R | 147 | 28, 0, −12 | 3.43 | 0.009 | Passive | BD>HC** | |
Anger | ||||||||
Passive | BD>HC* | |||||||
Neutral | ||||||||
ACC | 32 | R | 972 | 4, 26, 34 | 3.63 | 0.029 | Explicit (Afraid) | HC>BD* |
Anger | ||||||||
Implicit (Nose width) | HC>BD*** | |||||||
Anger | ||||||||
Implicit (Nose width) | HC>BD* | |||||||
Happy | ||||||||
Implicit (Nose width) | HC>BD** | |||||||
Neutral | ||||||||
Passive | BD>HC** | |||||||
Anger | ||||||||
IFG | 45/47 | R | 159 | 34, 24, −12 | 3.59 | 0.021 | Implicit (Nose width) | HC>BD* |
Happy | ||||||||
Implicit (Nose width) | HC>BD* | |||||||
Neutral | ||||||||
Putamen | L | 471 | −30, −8, −8 | 3.72 | 0.009 | Explicit (Hostility) | HC>BD** | |
Happy | ||||||||
Passive | BD>HC* | |||||||
Anger | ||||||||
Passive | BD>HC* | |||||||
Neutral |
ACC, Anterior cingulate cortex; IFG, inferior frontal gyrus; BA, Brodmann area; BD, bipolar disorder; HC, healthy comparisons; R, right; L, left.
p<0.05,
p<0.01,
p<0.001.