Table 1. Patient demographics and baseline values of studied parameters.
| Total CF patient group | Non-exacerbating (no PE) | Exacerbating (PE) | p-value no PE vs. PE | ||
| Demographics | Number of patients | 52 | 15 | 37 | |
| Sex (F/M) | 24/28 | 5/10 | 19/18 | 0.358 | |
| Age | 32.8 (1.8) | 36.1 (3.4) | 31.5 (2.3) | 0.112 | |
| Age range | 18–64 | 18–59 | 18–64 | ||
| Weight (kg) | 60.8 (2.1) | 64.9 (2.8) | 59.1 (2.6) | 0.031* | |
| BMI (kg/m2) (NR: 18.5–24.9) | 21.9 (0.6) | 23.4 (0.7) | 21.3 (0.7) | 0.009* | |
| Clinical assessments | FEV1% predicted (%) | 63.0 (3.8) | 78.5 (5.0) | 56.8 (4.6) | 0.009* |
| FVC% predicted (%) | 79.8 (3.7) | 95.1 (5.2) | 73.6 (4.4) | 0.008* | |
| White blood cells (109/L) (NR: 4.8–10.8) | 9.4 (0.4) | 8.1 (0.6) | 10.0 (0.4) | 0.018* | |
| Neutrophils (109/L) (NR: 1.6–7.7) | 6.7 (0.3) | 5.6 (0.5) | 7.1 (0.4) | 0.033* | |
| Eosinophils (109/L) (NR: 0.0–0.5) | 0.2 (0.02) | 0.2 (0.07) | 0.2 (0.01) | 0.562 | |
| Platelets (109/L) (NR: 140–440) | 284.6 (8.4) | 244.0 (14.6) | 301.6 (9.0) | 0.001* | |
| Matouk Disease Score | Clinical (0–50 points) | 36.3 (0.6) | 39.3 (1.0) | 35.1 (0.7) | 0.002* |
| PFT (0–25 points) | 16.6 (0.9) | 19.9 (1.1) | 15.2 (1.0) | 0.018* | |
| CXR (0–25 points) | 16.5 (0.4) | 18.2 (0.9) | 15.8 (0.4) | 0.008* | |
| Complication (0–37 points) | 2.6 (0.5) | 0.3 (0.2) | 3.5 (0.7) | 0.000* | |
| Total | 66.9 (2.0) | 77.3 (2.3) | 62.6 (2.4) | 0.001* | |
| Quality of life | Weight | 64.1 (5.2) | 84.5 (5.5) | 55.9 (6.5) | 0.016* |
| Respiratory | 68.3 (2.3) | 74.8 (4.5) | 65.6 (2.6) | 0.072 | |
| Digestion | 78.0 (2.5) | 84.5 (4.0) | 75.4 (3.1) | 0.064 | |
| Physical | 71.8 (3.4) | 83.3 (3.8) | 67.2 (4.4) | 0.041* | |
| Vitality | 64.4 (2.2) | 67.8 (4.4) | 63.1 (2.6) | 0.341 | |
| Emotion | 81.7 (2.2) | 90.7 (2.6) | 78.0 (2.7) | 0.008* | |
| Eating | 90.3 (2.3) | 91.1 (4.8) | 89.9 (2.7) | 0.537 | |
| Treatment burden | 66.2 (3.4) | 74.8 (6.7) | 62.8 (3.9) | 0.113 | |
| Health Perceptions | 69.5 (2.8) | 80.8 (4.0) | 54.9 (3.3) | 0.009* | |
| Body Image | 73.5 (3.5) | 88.9 (3.1) | 67.3 (4.3) | 0.004* | |
| Social | 74.6 (2.5) | 81.5 (4.4) | 71.8 (2.9) | 0.074 | |
| Role | 82.8 (2.8) | 91.7 (3.0) | 79.2 (3.6) | 0.044* | |
| Total (0–1200 points) | 885.2 (21.8) | 994.2 (28.9) | 841.0 (25.1) | 0.001* |
Data represented as mean (SEM). * p-value designates significant statistical difference between non-exacerbating (no PE) and exacerbating patients (PE) using Student's t-test or Mann-Whitney t-test when values were not normally distributed. NR indicates normal range for cell counts. BMI normal range from Health Canada (http://www.hc-sc.gc.ca).