Table 4. Markers associated with early re-exacerbation at the end of PE treatment.
Early PE (n = 6) | Late PE (n = 6) | p- value | |
Days until next PE mean (min – max) | 17.3 (1–29) | 142.5 (56–365) | N/A |
FEV1% predicted (%) | 38.5 (7.2) | 50.0 (8.5) | 0.328 |
FVC% predicted (%) | 56.5 (9.9) | 64.0 (10.0) | 0.606 |
Matouk Total score | 46.5 (6.2) | 56.8 (3.7) | 0.180 |
QOL Total score | 752.0 (86.7) | 765.5 (62.8) | 0.902 |
CRP (mg/L) | 42.5 (26.1) | 5.2 (2.7) | 0.045* |
IL-6 (pg/ml) | 4.9 (1.6) | 2.6 (0.6) | 0.199 |
IL-8 (pg/ml) | 3.9 (0.4) | 2.7 (0.3) | 0.034* |
IL-10 (pg/ml) | 24.4 (2.5) | 77.0 (37.8) | 0.195 |
Data presented as mean (SEM) unless specified. * indicates significant difference between the groups using Student's t-test or Mann-Whitney test if values were not normally distributed.