Table 1. Characterisation of CKD vs. control (CON) rats: organ weights, clinical signs and renal injury.

	CON	CKD
N	13	18
Body weight (BW) g	560±14	540±11
Total renal weight (mg/100 g BW)	664±13	591±10 ###
Heart weight (mg/100 g BW)	244±5	280±14 #
Total wet lung weight (mg/100 g BW)	309±6	337±6 ##
Diuresis (ml/24 h/100 g)	3.15±0.3	5.45±0.68 #
Proteinuria (mg/24 h)	16±4	152±9###
Hematocrit (%)	45.2±0.3	42.6±0.5 ###
Plasma urea (mmol/L)	6.76±0.18	10.47±0.38 ###
Plasma creatinine (µmol/L)	34±4	50±6 #
Plasma Na (mmol/L)	146.6±1.5	145.7±1.3
Plasma K (mmol/L)	4.25±0.12	4.22±0.07

Mean ± SEM, t-test: # P<0.05, ##P<0.01, ###P<0.001 vs. CON.