Table 2. Metabolic profile of multi-low dose, streptozotocin/high-fat diet mice treated with XMetS and controls.

	Non-diabetic+control IgG	Diabetic+control IgG	Diabetic+XMetS
Body Weight (g)	42.5±3.1*	35.5±3.2	38.4±2.3*
Beta hydroxybutyrate (mmol/L)	0.26±0.05*	4.79±1.8	1.05±0.61*
Glucose (mg/dL)	113±19*	488±40	183±20*
Total cholesterol (mg/dL)	154±17*	175±29	159±31
Non-HDL cholesterol (mg/dL)	34±10*	101±32	63±21*
Insulin (pg/mL)	1006±332*	336±301	137±51*
C-peptide (pM)	204±69*	142±67	67±63*

At the end of the 6-week study with multi-low dose, streptozotocin/high-fat diet mice, the animals were fasted 14 hours, weighed and plasma was obtained to determine the above parameters. Mice (n = 8/group) were treated with antibody at 10 mg/kg, twice weekly. Values are shown as mean ± SEM. *p<0.05 vs. diabetic+control IgG.