Table 2.

Genome-Wide Association Results with q-values < 0.10

Phenotype	Antipsychotic	Gene symbol	Cytogenetic location	Psn(bp)	SNP number	MAF	MA	Eff	n	p-value	q-value
CGI-S	Olanzapine	ATP1A2	1q23.2	156890927	rs6688363	0.166	T	+	263	1.59E-07	0.078
	Risperidone		16q22.1	64716237	rs8050896	0.161	T	−	267	3.85E-08	0.019
		TNFRSF11A	18q21.3	58231092	rs2980976	0.168	A	+	268	2.97E-07	0.060
		PPA2	4q24	106655117	rs2636697	0.038	G	+	268	3.68E-07	0.060
				106710973	rs2636719	0.039	A	+	265	5.05E-07	0.062
	Ziprasidone		11q14.1	79736127	rs7395555	0.145	C	−	188	1.98E-07	0.098
PGI	Olanzapine	SPOPL	2q22.1	139112654	rs10170310	0.213	G	+	264	1.03E-07	0.051
	Quetiapine	PDE4D	5q12.1	59015703	rs17382202	0.153	T	−	263	4.21E-08	0.021
				59034799	rs17742120	0.161	G	−	265	1.58E-07	0.031
				59047264	rs2164660	0.161	A	−	257	1.87E-07	0.031
	Risperidone	TJP1	15q13.1	27980760	rs711355	0.330	T	−	267	2.25E-07	0.081
				27980608	rs785423	0.402	A	−	265	4.86E-07	0.081
				27961668	rs813676	0.401	T	−	264	4.91E-07	0.081

Abbreviations: Psn, position; MAF, minor allele frequency; MA, minor allele; Eff, direction of the effect of minor allele; n, sample size. For each test, we report n, Eff (where a ‘+’ indicates global impression severity score positively associated with minor allele count), and the p- and q-values of the test. Shaded rows indicate SNPs in high linkage disequilibrium (r² > 0.8) with each other.