Table 3.
Results of the in silico analyses and the Spearman rank correlation
|
miRNA |
Target gene |
||||
|---|---|---|---|---|---|
| AMACR | EZH2 | PSGR | PSMA | TRPM8 | |
| miR-101 |
|
8x |
|
|
|
| |
−0.156# |
|
|
|
|
| miR-138 |
1x |
7x |
|
|
|
| −0.256** |
−0.215* |
|
|
|
|
| miR-186 |
2x |
|
|
4x |
|
| −0.551** |
|
|
−0.418** |
|
|
| miR-224 |
4x |
|
|
|
|
| −0.384** |
|
|
|
|
|
| miR-26a |
1x |
6x |
|
1x |
3x |
| −0.335** |
−0.383** |
|
−0.237** |
−0.362** |
|
| miR-26b |
1x |
6x |
|
|
3x |
| −0.154# |
−0.141 |
|
|
−0.107 |
|
| miR-374a |
|
|
2x |
3x |
3x |
| |
|
−0.230** |
−0.248** |
−0.329** |
|
| miR-410 |
1x |
1x |
2x |
2x |
1x |
| −0.273** |
−0.293** |
−0.283** |
−0.239** |
−0.395** |
|
| miR-660 |
3x |
|
|
3x |
|
| −0.241** | −0.289** | ||||
In the upper rows the respective numbers of predictions out of eight possible algorithms are denoted. In the lower rows results of the Spearman rank correlation expressed as Spearman correlation coefficients are displayed. The relative transcript levels of the target genes and the miRNAs in all tissue samples (Tu, Tf, BPH) were used for the calculation of the Spearman correlation coefficients. Empty cells indicate that there was no prediction by any algorithm in the in silico analyses. *p < 0.05, **p < 0.01, #p < 0.1 (statistical trend).