Table 4.
Differentially expressed miRNAs between malignant and non-malignant prostate tissues samples
|
miRNA |
Median relative transcript levels (x10
-3
) |
Median fold expressions |
|||
|---|---|---|---|---|---|
| |
Tu |
Tf |
BPH |
Tu
vs
Tf
[median]
|
Tu
vs
BPH
[median]
|
| (n = 50) | (n = 46) | (n = 30) | |||
| miR-101 |
1.52 |
2.91 |
2.01 |
−1.92** |
−1.32 |
| miR-138 |
0.19 |
1.08 |
1.06 |
−5.61** |
−5.49** |
| miR-186 |
39.52 |
138.59 |
160.43 |
−3.51** |
−4.06** |
| miR-224 |
1.19 |
4.12 |
3.22 |
−3.45** |
−2.70** |
| miR-26a |
179.04 |
380.81 |
310.84 |
−2.13** |
−1.74** |
| miR-26b |
51.77 |
69.98 |
60.60 |
−1.35 * |
−1.17 |
| miR-374a |
17.63 |
39.65 |
33.84 |
−2.25** |
−1.92** |
| miR-410 |
0.08 |
0.28 |
0.33 |
−3.64** |
−4.29** |
| miR-660 | 13.46 | 22.50 | 22.63 | −1.67** | −1.68** |
Depicted are the median relative transcript levels of the evaluated miRNAs (normalized to RNU48) in Tu, matched Tf and BPH tissue samples as well as the median fold expressions of the Tu samples compared to the indicated control group. P values were calculated by the Mann–Whitney U test with a two-sided 95% confidence interval (*p < 0.05, **p < 0.01).