Table 1. Male participant characteristics by quartiles of immunoglobulin M (n = 5,673)a.
| Quartiles of immunoglobulin M (range, mg/dL) | |||||
| Level 1 (7.2–59.2) | Level 2 (59.3–80.6) | Level 3 (80.7–108.0) | Level 4 (109.0–2080.0) | P for trendb | |
| (n = 1,422) | (n = 1,415) | (n = 1,406) | (n = 1,430) | ||
| Age (y) | 48.5 (27.0, 81.0)c | 45.7 (25.0, 85.0)d | 45.6 (26.0, 86.0)d | 45.4 (25.0, 85.0)d | <0.0001 |
| BMI (kg/m2) | 26.3 (17.3, 45.2) | 26.3 (16.5, 51.1) | 26.0 (16.6, 44.6)d | 25.8 (15.4, 38.3)d | <0.01 |
| Waist circumference (cm) | 91.5 (67.0, 125.0) | 91.1 (64.0, 133.0) | 90.2 (63.0, 135.0)d | 89.8 (63.0, 124.0)d | <0.001 |
| TC (mmol/L) | 5.24 (2.72, 10.06) | 5.26 (2.97, 9.96) | 5.26 (2.05, 10.42) | 5.25 (2.99, 15.45) | 0.55 |
| TG (mmol/L) | 1.92 (0.41, 19.81) | 1.98 (0.32, 16.04) | 2.06 (0.37, 17.71) | 2.20 (0.36, 28.35)d | 0.02 |
| LDL (mmol/L) | 3.15 (1.09, 7.06) | 3.17 (0.81, 7.98) | 3.17 (0.63, 8.00) | 3.16 (1.19, 10.45) | 0.51 |
| HDL (mmol/L) | 1.30 (0.30, 2.74) | 1.27 (0.62, 2.75) | 1.28 (0.51, 2.71) | 1.26 (0.46, 2.60)d | 0.08 |
| SBP (mmHg) | 126.6 (90.0, 205.0) | 125.9 (90.0, 205.0) | 125.3 (85.0, 190.0) | 124.2 (80.0, 180.0)d | 0.03 |
| DBP (mmHg) | 82.6 (50.0, 125.0) | 82.3 (50.0, 130.0) | 81.7 (50.0, 125.0) | 81.2 (50.0, 125.0)d | 0.0504 |
| FBS (mmol/L) | 5.45 (3.60, 19.20) | 5.32 (3.60, 15.40) | 5.36 (3.50, 20.20) | 5.28 (3.50, 19.10)d | 0.07 |
| IgA (mg/dL) | 226.5 (8.1, 657.0) | 235.3 (51.8, 690.0) | 236.1 (41.2, 745.0) | 246.3 (6.7, 718.0)d | <0.01 |
| IgG (mg/dL) | 1090.5 (517.0, 3330.0) | 1132.0 (420.0, 2340.0)d | 1145.0 (447.0, 2020.0)d | 1187.6 (55.4, 2330.0)d | <0.0001 |
| Smoking status (%) | |||||
| Smoker | 50.8 | 49.1 | 46.3 | 49.4 | 0.31 |
| Ex-smoker | 0.14 | 0.21 | 0.36 | 0.21 | 0.60 |
| Drinker (%) | 68.5 | 67.2 | 66.0 | 65.8 | 0.11 |
| Family history of diseases (%) | |||||
| CVD | 33.8 | 30.3 | 29.3 | 27.8 | <0.001 |
| Hypertension | 46.6 | 46.4 | 44.9 | 43.8 | 0.09 |
| Hyperlipidemia | 0.21 | 0.64 | 0.28 | 0.14 | 0.30 |
| Diabetes | 20.1 | 19.2 | 18.2 | 17.3 | 0.045 |
a
BMI, body mass index; TC, total cholesterol; TG, triglycerides; LDL, low density lipoprotein cholesterol; HDL, high-density lipoprotein-cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBS, fasting blood sugar; UA, uric acid; CVD, cardiovascular disease; Ig, immunoglobulin.
b
Analysis of variance or logistic regression analysis.
c
Mean (range) (all such values).
d
Significantly different from the lowest quartile of immunoglobulin M (Bonferroni correction): P<0.05.