Table 2. Female participant characteristics by quartiles of immunoglobulin M (n = 3,706)a.
| Quartiles of immunoglobulin M (range, mg/dL) | |||||
| Level 1 (7.2–80.8) | Level 2 (80.9–111.0) | Level 3 (112.0–152.0) | Level 4 (153.0–2480.0) | P for trend b | |
| (n = 927) | (n = 942) | (n = 900) | (n = 937) | ||
| Age (y) | 51.3 (26.0, 84.0)c | 47.7 (27.0, 81.0)d | 45.1 (25.0, 83.0)d | 44.2 (28.0, 76.0)d | <0.0001 |
| BMI (kg/m2) | 25.0 (16.4, 45.5) | 24.3 (16.0, 36.5)d | 23.8 (11.6, 40.0)d | 23.5 (16.2, 36.1)d | <0.0001 |
| Waist circumference (cm) | 82.3 (60.0, 127.0) | 80.4 (56.0, 115.0)d | 78.4 (51.0, 109.0)d | 77.6 (57.0, 112.0)d | <0.0001 |
| TC (mmol/L) | 5.41 (3.10, 8.71) | 5.32 (3.09, 9.67) | 5.20 (2.80, 10.34)d | 5.14 (2.89, 11.32)d | <0.0001 |
| TG (mmol/L) | 1.45 (0.33, 7.05) | 1.36 (0.35, 10.27) | 1.27 (0.37, 11.07)d | 1.31 (0.32, 23.74)d | <0.0001 |
| LDL (mmol/L) | 3.26 (0.70, 6.11) | 3.19 (1.35, 7.44) | 3.11 (1.12, 7.87)d | 3.05 (1.17, 7.77)d | <0.001 |
| HDL (mmol/L) | 1.51 (0.72, 3.17) | 1.54 (0.62, 2.94) | 1.54 (0.74, 2.86) | 1.53 (0.73, 2.99) | 0.10 |
| SBP (mmHg) | 126.1 (80.0, 200.0) | 121.8 (80.0, 185.0)d | 119.2 (80.0, 190.0)d | 118.3 (80.0, 180.0)d | <0.0001 |
| DBP (mmHg) | 77.2 (50.0, 115.0) | 75.3 (50.0, 110.0)d | 74.6 (50.0, 110.0)d | 74.4 (50.0, 125.0)d | <0.0001 |
| FBS (mmol/L) | 5.22 (3.30, 22.70) | 4.99 (3.60, 14.20)d | 4.98 (3.40, 14.30)d | 4.96 (3.30, 16.50)d | <0.0001 |
| IgA (mg/dL) | 234.5 (51.6, 1230.0) | 231.4 (6.7, 651.0) | 230.1 (65.3, 716.0) | 239.0 (71.4, 1140.0) | 0.33 |
| IgG (mg/dL) | 1213.6 (637.0, 2490.0) | 1229.4 (599.0, 2240.0) | 1260.0 (665.0, 2590.0)d | 1273.7 (49.8, 2650.0)d | <0.0001 |
| Smoking status (%) | |||||
| Smoker | 5.5 | 6.2 | 3.8 | 3.6 | <0.01 |
| Ex-smoker | 0.00 | 0.00 | 0.00 | 0.00 | - |
| Drinker (%) | 13.4 | 13.8 | 14.3 | 14.7 | 0.37 |
| Family history of diseases (%) | |||||
| CVD | 34.8 | 31.5 | 30.6 | 27.6 | 0.001 |
| Hypertension | 44.4 | 46.9 | 47.3 | 46.2 | 0.52 |
| Hyperlipidemia | 0.32 | 0.85 | 0.22 | 0.43 | 0.69 |
| Diabetes | 19.2 | 17.8 | 18.2 | 16.4 | 0.16 |
a
BMI, body mass index; TC, total cholesterol; TG, triglycerides; LDL, low density lipoprotein cholesterol; HDL, high-density lipoprotein-cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBS, fasting blood sugar; UA, uric acid; CVD, cardiovascular disease; Ig, immunoglobulin.
b
Analysis of variance or logistic regression analysis.
c
Mean (range) (all such values).
d
Significantly different from the lowest quartile of immunoglobulin M (Bonferroni correction): P<0.05.