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. 2014 Feb 6;2(2):180–188. doi: 10.1016/j.stemcr.2014.01.001

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© 2014 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Identification of Coregulated Genes

(A) Selection of differentially expressed probes between SC and CB (p < 0.01; log² fold change ≥ 0.75) are represented as black dots in the Birnie et al. (2008) microarray data.

(B) Differentially expressed probes were clustered in distinct A–D groups on coexpression analysis. Principal GO terms enriched for groups B and C are shown below the group name. Group A was not enriched for any GO terminology, whereas group C was enriched for genes involved in (lens) development.

(C) Normalized expression of group A–D probes. Probes overexpressed in committed basal cells (CB) are above the horizontal line at 0 (groups A and C) and probes overexpressed in stem-like cells (SC) (groups B and D) are below the line. Boxplot shows minimum, 25%, median, 75%, and maximum.