Figure 2.

Genes in Groups A–D Are Coexpressed in the Majority of Human Cell Types

(A) Overview of the composition of compendium data set.

(B) Schematic representation of the methodology for the compendium data set.

(C) Correlation of coexpression of genes in groups A–D compared to all genes in the compendium data set. All the groups are significantly different where the p value is computationally indistinguishable from zero.

(D) Expression of candidate group C genes in the Birnie et al. (2008) microarray data. BS, benign stem-like cells; MS, malignant stem-like cells; BC, benign committed basal cells; MC, malignant committed basal cells.

(E) Western blot analysis of LCN2, CEACAM6, and S100P expression. Representative image, n = 6 each for benign prostatic hyperplasia (BPH) and treatment-naïve prostate cancer (PCa) (biological replicates).

(F) Rainbow contour graphs for the correlation of coexpression for TMPRSS2, CEACAM6, LCN2, and S100P with each other in compendium data set. Values at the top of each square indicate correlation coefficient. All values are significant with p < 0.05.

All boxplots show minimum, 25%, median, 75%, and maximum. See also Figure S1 and Table S1.