Table 4.
Top 20 Vienna7 vs. wild Hawaiian type differentially regulated genes GO term enrichment
| Term | Annotated | Significant | Expected | Fisher exact test | p-value |
|---|---|---|---|---|---|
|
Up-regulated genes
| |||||
| GO:1901360 |
Organic cyclic compound metabolic processes |
1289 |
130 |
81.06 |
6.70E-11 |
| GO:0090304 |
Nucleic acid metabolic process |
948 |
105 |
59.61 |
7.10E-11 |
| GO:0006259 |
DNA metabolic process |
239 |
42 |
15.03 |
3.50E-10 |
| GO:0006725 |
Cellular aromatic compound metabolism |
1231 |
123 |
77.41 |
7.40E-10 |
| GO:0006396 |
RNA processing |
166 |
33 |
10.44 |
1.30E-09 |
| GO:0006139 |
Nucleobase-containing compound metabolism |
1166 |
117 |
73.32 |
2.20E-09 |
| GO:0046483 |
Heterocycle metabolic process |
1212 |
120 |
76.21 |
2.80E-09 |
| GO:0044260 |
Cellular macromolecule metabolic process |
1441 |
135 |
90.61 |
5.50E-09 |
| GO:0090305 |
Nucleic acid phosphodiester bond hydroly… |
78 |
21 |
4.9 |
5.70E-09 |
| GO:0019079 |
Viral genome replication |
13 |
9 |
0.82 |
7.70E-09 |
| GO:0042254 |
Ribosome biogenesis |
60 |
18 |
3.77 |
1.10E-08 |
| GO:0034660 |
NcRNA metabolic process |
74 |
20 |
4.65 |
1.30E-08 |
| GO:0034641 |
Cellular nitrogen compound metabolic pro… |
1291 |
123 |
81.18 |
1.90E-08 |
| GO:0022613 |
Ribonucleoprotein complex biogenesis |
73 |
19 |
4.59 |
5.70E-08 |
| GO:0006260 |
DNA replication |
93 |
21 |
5.85 |
1.60E-07 |
| GO:0044237 |
Cellular metabolic process |
2258 |
181 |
141.99 |
3.90E-07 |
| GO:0019058 |
Viral infectious cycle |
18 |
9 |
1.13 |
4.00E-07 |
| GO:0034470 |
NcRNA processing |
53 |
15 |
3.33 |
4.60E-07 |
| GO:0006807 |
Nitrogen compound metabolic process |
1455 |
128 |
91.49 |
1.30E-06 |
| GO:0006281 |
DNA repair |
82 |
17 |
5.16 |
8.90E-06 |
|
Down-regulated genes
|
|
|
|
|
|
| GO:0048468 |
Cell development |
610 |
94 |
42.38 |
1.30E-15 |
| GO:0048646 |
Anatomical structure formation |
662 |
95 |
45.99 |
9.90E-14 |
| GO:0051239 |
Regulation of multicellular organismal processes |
413 |
67 |
28.69 |
5.00E-12 |
| GO:0030182 |
Neuron differentiation |
331 |
58 |
23 |
7.30E-12 |
| GO:0003008 |
System process |
462 |
70 |
32.1 |
4.20E-11 |
| GO:0030154 |
Cell differentiation |
927 |
112 |
64.41 |
4.60E-11 |
| GO:0009653 |
Anatomical structure morphogenesis |
761 |
97 |
52.87 |
8.80E-11 |
| GO:0048869 |
Cellular developmental process |
964 |
114 |
66.98 |
1.20E-10 |
| GO:0050877 |
Neurological system process |
385 |
61 |
26.75 |
1.60E-10 |
| GO:0048699 |
Generation of neurons |
356 |
58 |
24.73 |
1.60E-10 |
| GO:0007267 |
Cell-cell signaling |
264 |
48 |
18.34 |
1.70E-10 |
| GO:0044767 |
Single-organism developmental process |
1185 |
131 |
82.33 |
2.40E-10 |
| GO:0048513 |
Organ development |
697 |
90 |
48.43 |
2.90E-10 |
| GO:0007423 |
Sensory organ development |
191 |
39 |
13.27 |
3.20E-10 |
| GO:0023052 |
Signaling |
980 |
114 |
68.09 |
3.50E-10 |
| GO:0044700 |
Single organism signaling |
980 |
114 |
68.09 |
3.50E-10 |
| GO:0048749 |
Compound eye development |
122 |
30 |
8.48 |
3.90E-10 |
| GO:0044707 |
Single-multicellular organism process |
1699 |
169 |
118.04 |
4.10E-10 |
| GO:0007154 |
Cell communication |
996 |
115 |
69.2 |
4.50E-10 |
| GO:0042692 | Muscle cell differentiation | 123 | 30 | 8.55 | 4.80E-10 |