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. 2014 Feb 5;15:98. doi: 10.1186/1471-2164-15-98

Table 6.

Vienna7 adults vs. wild Hawaiian wild-type adults differentially regulated genes GO term enrichment

Term Annotated Significant Expected Fisher exact test p-value
Up-regulated genes
GO:0044260
Cellular macromolecule metabolic process
1441
270
190.73
7.90E-14
GO:0006396
RNA processing
166
56
21.97
3.50E-12
GO:0044237
Cellular metabolic process
2258
372
298.87
1.40E-11
GO:0022613
Ribonucleoprotein complex biogenesis
73
31
9.66
4.60E-10
GO:0043170
Macromolecule metabolic process
1839
311
243.41
5.20E-10
GO:0008152
Metabolic process
2745
425
363.33
1.40E-09
GO:0034660
ncRNA metabolic process
74
30
9.79
3.40E-09
GO:0071704
Organic substance metabolic process
2587
403
342.41
6.90E-09
GO:0042254
Ribosome biogenesis
60
26
7.94
7.30E-09
GO:0006364
rRNA processing
35
19
4.63
8.00E-09
GO:0034470
ncRNA processing
53
24
7.02
9.60E-09
GO:0016072
rRNA metabolic process
36
19
4.76
1.50E-08
GO:0044238
Primary metabolic process
2432
382
321.9
1.70E-08
GO:0090304
Nucleic acid metabolic process
948
175
125.48
1.20E-07
GO:0006457
Protein folding
52
22
6.88
1.80E-07
GO:0034641
Cellular nitrogen compound metabolism
1291
221
170.88
8.10E-07
GO:0046483
Heterocycle metabolic process
1212
209
160.42
1.20E-06
GO:0006725
Cellular aromatic compound metabolism
1231
211
162.93
1.60E-06
GO:0006139
Nucleobase-containing compound metabolism
1166
201
154.33
2.30E-06
GO:0044267
Cellular protein metabolic process
609
118
80.61
2.50E-06
GO:1901360
Organic cyclic compound metabolism
1289
218
170.61
2.90E-06
GO:0006974
Response to DNA damage stimulus
136
38
18
3.00E-06
GO:0000075
Cell cycle checkpoint
44
18
5.82
4.30E-06
GO:0031570
DNA integrity checkpoint
33
15
4.37
5.80E-06
GO:0030163
Protein catabolic process
110
32
14.56
7.30E-06
GO:0044265
Cellular macromolecule catabolic process
143
38
18.93
1.10E-05
GO:0071156
Regulation of cell cycle arrest
47
18
6.22
1.30E-05
GO:0000077
DNA damage checkpoint
28
13
3.71
1.90E-05
GO:0009451
RNA modification
18
10
2.38
2.50E-05
GO:0007050
Cell cycle arrest
58
20
7.68
2.70E-05
GO:0016071
mRNA metabolic process
122
33
16.15
2.80E-05
GO:0051603
Proteolysis involved in cellular protein…
88
26
11.65
4.00E-05
GO:0006807
Nitrogen compound metabolic process
1455
234
192.58
5.70E-05
GO:0006270
DNA replication initiation
10
7
1.32
5.70E-05
GO:0044257
Cellular protein catabolic process
90
26
11.91
6.10E-05
GO:0019079
Viral genome replication
13
8
1.72
6.30E-05
GO:0007093
Mitotic cell cycle checkpoint
31
13
4.1
7.00E-05
GO:0022403
Cell cycle phase
246
54
32.56
7.10E-05
GO:0009057
Macromolecule catabolic process
201
46
26.6
8.70E-05
GO:0010389
Regulation of G2/M transition of mitotic…
28
12
3.71
0.0001
GO:0051329
Interphase of mitotic cell cycle
73
22
9.66
0.00011
Down-regulated genes
GO:0071482
Cellular response to light stimulus
14
11
1.59
9.80E-09
GO:0007603
Phototransduction, visible light
10
9
1.14
2.70E-08
GO:0016056
Rhodopsin mediated signaling pathway
10
9
1.14
2.70E-08
GO:0048646
Anatomical structure formation involved…
662
118
75.31
4.80E-08
GO:0007600
Sensory perception
142
39
16.15
6.40E-08
GO:0009583
Detection of light stimulus
29
15
3.3
9.60E-08
GO:0009584
Detection of visible light
19
12
2.16
9.80E-08
GO:0042692
Muscle cell differentiation
123
35
13.99
1.20E-07
GO:0001539
Ciliary or flagellar motility
11
9
1.25
1.30E-07
GO:0051239
Regulation of multicellular organismal processes
413
81
46.98
1.70E-07
GO:0003008
System process
462
88
52.55
1.90E-07
GO:0009581
Detection of external stimulus
38
17
4.32
2.00E-07
GO:0016059
Deactivation of rhodopsin mediated signa…
9
8
1.02
2.20E-07
GO:0022400
Regulation of rhodopsin mediated signali…
9
8
1.02
2.20E-07
GO:0009582
Detection of abiotic stimulus
39
17
4.44
3.20E-07
GO:0055002
Striated muscle cell development
86
27
9.78
4.00E-07
GO:0007602
Phototransduction
21
12
2.39
4.60E-07
GO:0055001
Muscle cell development
92
28
10.47
5.00E-07
GO:0030239
Myofibril assembly
36
16
4.1
5.10E-07
GO:0061061
Muscle structure development
174
42
19.79
9.80E-07
GO:0050953
Sensory perception of light stimulus
70
23
7.96
1.20E-06
GO:0051606
Setection of stimulus
48
18
5.46
2.10E-06
GO:0071478
Cellular response to radiation
20
11
2.28
2.40E-06
GO:0007018
Microtubule-based movement
53
19
6.03
2.40E-06
GO:0007601
Visual perception
68
22
7.74
2.80E-06
GO:0050877
Neurological system process
385
73
43.8
3.00E-06
GO:0048468
Cell development
610
104
69.39
3.70E-06
GO:0009653
Anatomical structure morphogenesis
761
124
86.57
3.80E-06
GO:0044707
Single-multicellular organism process
1699
239
193.27
4.80E-06
GO:0051146
Striated muscle cell differentiation
108
29
12.29
5.40E-06
GO:0030182
Neuron differentiation
331
64
37.65
6.90E-06
GO:0032501
Multicellular organismal process
1737
242
197.59
9.10E-06
GO:0031032
Actomyosin structure organization
44
16
5.01
1.20E-05
GO:0040011
Locomotion
380
70
43.23
1.40E-05
GO:0009416
Response to light stimulus
55
18
6.26
1.90E-05
GO:0032101
Regulation of response to external stimuli
55
18
6.26
1.90E-05
GO:0071214
Cellular response to abiotic stimulus
28
12
3.19
2.20E-05
GO:0007606
Sensory perception of chemical stimulus
56
18
6.37
2.50E-05
GO:0032989
Cellular component morphogenesis
362
66
41.18
3.70E-05
GO:0048699
generation of neurons
356
65
40.5
4.10E-05
GO:2000026 Regulation of multicellular organismal development 228 46 25.94 5.10E-05