Table 5.
Comparison of PSA kinetics between CK and CF-EBRT by Gleason score and age subsets: probability values
| Gleason score 3 + 3 | Gleason score 3 + 4 | ||
|---|---|---|---|
| |
Through year: |
|
|
| Nadir PSA (ng/mL) |
|
|
|
| |
1 |
ns |
ns |
| |
|
p = 0.01 |
p = 0.03 |
| |
|
p = 0.03 |
p = 0.02 |
| Time to Nadir PSA (mos.) |
|
|
|
| |
1 |
ns |
ns |
| |
2 |
ns |
ns |
| |
3 |
p = 0.02 |
ns |
| Rate of PSA change: ng/mL/month |
|
|
|
| |
1 |
ns |
ns |
| |
2 |
p = 0.02 |
ns |
| |
3 |
p = 0.01 |
ns |
| |
|
Age < 70 |
Age ≥ 70 |
| Nadir PSA (ng/mL) |
|
|
|
| |
1 |
ns |
ns |
| |
2 |
p = 0.002 |
p = 0.03 |
| |
3 |
p = 0.01 |
ns |
| Time to Nadir PSA (mos.) |
|
|
|
| |
1 |
ns |
ns |
| |
2 |
ns |
ns |
| |
3 |
p = 0.004 |
ns |
| Rate of PSA change: ng/mL/Month |
|
|
|
| |
1 |
ns |
ns |
| |
2 |
ns |
ns |
| 3 | (p = 0.09) | p = 0.03 |
For each Gleason score subset (3 + 3 vs 3 + 4) and age subset (<70 vs ≥70) the PSA outcomes were compared between SBRT and CF-EBRT. The distributions for PSA nadir and PSA slope were compared using the Mann–Whitney test. The distributions for the time to PSA nadir was compared using the log rank test. [ns: not significant].