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. 2014 Jan 15;12:4. doi: 10.1186/1477-5956-12-4

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Copyright © 2014 Wang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Glycopeptides/glycoproteins with inconsistent changes in the ConA, LCH, and WGA subgroups. (A) When comparing HCC patients with healthy individuals, five glycoproteins were altered inconsistently among the three lectin subgroups (ConA, LCH, and WGA); (B) When comparing the serum of HCC patients with that of healthy individuals, six glycopeptides changed discordantly among the three lectin subgroups (ConA, LCH, and WGA). Each column represents the percentage of the amount of glycopeptide/glycoprotein (HCC patients versus healthy individuals) in each lectin subgroup. Positive percentages denote upregulation, whereas negative percentages denote downregulation. Glycopeptide GLN*VTLSSTGR was from CO4A_HUMAN [Swiss-Prot:P0C0L4], LAN*LTQGEDQYYLR from CLUS_HUMAN [Swiss-Prot:P10909], ADGTVNQIEGEATPVN*LTEPAK from APOD_HUMAN [Swiss-Prot:P05090], ALGFEN*ATQALGR from LG3BP_HUMAN [Swiss-Prot:Q08380], SVTWSESGQN*VTAR from IGHA2_HUMAN [Swiss-Prot:P01877], and FSDGLESN*SSTQFEVK from CO4B_HUMAN [Swiss-Prot:P0C0L5]. Other glycoproteins were MUCB_HUMAN [Swiss-Prot:P04220] and VTNC_HUMAN [Swiss-Prot:P04004]. *denotes the N-glycosylation site.