Table 2.
Human seminal fluid protease inhibitors.
| Protease inhibitor class | Protein name | GI | Reference |
|---|---|---|---|
| Cysteine | |||
| Cystatin A | 48145945 | (Pilch and Mann 2006) | |
| Cystatin SN | 118188 | (Pilch and Mann 2006) | |
| CST6 | 74724686 | (Pilch and Mann 2006) | |
| Cystatin C | 4503107 | (Fung et al. 2004) | |
| Cystatin S | 4503109 | (Fung et al. 2004) | |
|
| |||
| Metalloprotease inhibitor | |||
| Tissue inhibitor of metalloproteinase 1 | 4507509 | (Pilch and Mann 2006) | |
| Tissue inhibitor of metalloproteinase 2 | 4507511 | (Pilch and Mann 2006) | |
| Tissue inhibitor of metalloproteinase 3 | 4507513 | (Pilch and Mann 2006) | |
|
| |||
| Peptidase inhibitor | |||
| Peptidase inhibitor 15 | 7705676 | (Pilch and Mann 2006) | |
|
| |||
| Serine | |||
| Alpha-1-antitrypsin | 1703025 | (Fung et al. 2004; Pilch and Mann 2006) | |
| Plasma serine protease inhibitor | 194018472 | (Fung et al. 2004) | |
| Acrosin-trypsin inhibitor | 123985 | (Pilch and Mann 2006) | |
| Alpha-1-antichymotrypsin | 112874 | (Pilch and Mann 2006) | |
| Alpha-2-antiplasmin | 112907 | (Pilch and Mann 2006) | |
| Amyloid-beta A4 protein | 112927 | (Pilch and Mann 2006) | |
| Amyloid-like protein 2 | 1703344 | (Pilch and Mann 2006) | |
| Angiotensinogen | 113880 | (Pilch and Mann 2006) | |
| Anosmin-1 | 134048661 | (Pilch and Mann 2006) | |
| Antileukoproteinase I | 113636 | (Pilch and Mann 2006) | |
| Antithrombin III | 113936 | (Pilch and Mann 2006) | |
| CD109 (TGF-beta-1-binding protein) | 117949389 | (Pilch and Mann 2006) | |
| Epididymal secretory protein E4 | 20141958 | (Pilch and Mann 2006) | |
| Inter-alpha-trypsin inhibitor heavy chain H5 | 187609608 | (Pilch and Mann 2006) | |
| Kallistatin | 68067608 | (Pilch and Mann 2006) | |
| Kunitz-type protease inhibitor 1 | 61252335 | (Pilch and Mann 2006) | |
| Kunitz-type protease inhibitor 3 | 152031689 | (Pilch and Mann 2006) | |
| Kunitz-type protease inhibitor 4 | 74749362 | (Pilch and Mann 2006) | |
| Maspin (serpin B5) | 229462757 | (Pilch and Mann 2006) | |
| Neuroserpin (serpin I1) | 3183087 | (Pilch and Mann 2006) | |
| PEBP-1 | 1352726 | (Pilch and Mann 2006) | |
| PEDF (serpin F1) | 313104314 | (Pilch and Mann 2006) | |
| Peptidase inhibitor 15 (SugarCrisp) | 74735410 | (Pilch and Mann 2006) | |
| Placental thrombin inhibitor (serpin B6) | 161784343 | (Pilch and Mann 2006) | |
| Plasma protease C1 inhibitor | 124096 | (Pilch and Mann 2006) | |
| Protein AMBP | 122801 | (Pilch and Mann 2006) | |
| Protein C inhibitor (serpin A5) | 322510122 | (Pilch and Mann 2006) | |
| Putative protease inhibitor WAP8 | 126302615 | (Pilch and Mann 2006) | |
| Squamous cell carcinoma antigen 1 (serpin B3) | 20141712 | (Pilch and Mann 2006) | |
| Thyroxine-binding globulin (serpin A7) | 1351236 | (Pilch and Mann 2006) | |
| Tissue factor pathway inhibitor 2 | 1351226 | (Pilch and Mann 2006) | |
| Transcortin (serpin A6) | 115851 | (Pilch and Mann 2006) | |
| SPINT3 | 189571689 | (Clauss et al. 2011) | |
| SPINT4 | 110626171 | (Clauss et al. 2011) | |
| SPINT5 (sequence only available from mouse) | 53794664 | (Clauss et al. 2011) | |
Protease inhibitors identified in human seminal plasma, listed by protease inhibitor class. Protease classes are based either on experimental data or computational prediction. GI: NCBI identifier.