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. Author manuscript; available in PMC: 2014 Feb 13.
Published in final edited form as: Prostate. 2013 Feb 19;73(10):1069–1081. doi: 10.1002/pros.22654

Fig. 2.

Fig. 2

DHT acting on prostate tumor cells further enhances TCM-induced cell proliferation in MECs. In (A,B), MECs were seeded in 96-well plate and treated with TCMs collected from LAPC-4 and LNCaP cells treated with vehicle control (0), or DHT as indicated for 48 hr. In (C) MECs were treated with DHT at doses ranging from 0.1 to 50 nM for 48 hr. The data are the means ± SEM of four independent triplicate experiments. (D) is a representative RT-PCR analysis of mouse AR gene expression in MECs. Mouse testis (mTestis) and tRNA were used as positive and negative control, respectively. **P < 0.01 and *P < 0.05 compared to untreated control; ##P < 0.01 and #P < 0.05 compared to TCM-vehicle control.