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. Author manuscript; available in PMC: 2014 May 7.
Published in final edited form as: Nature. 2013 Oct 23;503(7474):72–77. doi: 10.1038/nature12630

Figure 3. Individuals with SHANK3 duplications have hyperkinetic disorders.

Figure 3

a, Array plot of an exon-targeted chromosome microarray analysis on DNA from an 11-year old female with ADHD, seizures and aberrant behaviors. Black dots indicate probes with normal copy number, while green dots indicate copy number gain. Solid and dotted lines define the minimum and maximum expected boundaries of the duplication, respectively. b, Array plot of the 35-year old male with bipolar disorder and epilepsy.