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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Anal Biochem. 2013 Dec 12;448:68–74. doi: 10.1016/j.ab.2013.12.008

Fig. 2.

Fig. 2

The dose response curves of the sigma-2 ligands in cell viability assay and caspase-3 activation assay. EMT-6 cells (A and B) or MDA-MB-435 cells (C and D) were treated with increasing concentrations of SV119 (○), siramesine (●), WC-26 (□), or RHM-1 (■) for 24 h. The cell viability and caspase-3 activation were then determined by MTS assay (A and C) and caspase-3 assay (B and D), respectively. The bars represent mean ± SD in the representative experiment performed in triplicates.