Figure 2. ^LytEnvC secondary structure map and sequence alignment with other LytM domains.

The secondary structure elements found in the^LytEnvC structure are indicated above the sequence alignment. Residue numbering is for EnvC.^LytEnvC residues important for function are highlighted with a red star.^LytEnvC residues selected for mutagenesis but resulting in unstable mutant proteins are highlighted with a black star. Residues required for^SaLytM catalysis are indicated by a blue star. Residues that are conserved or similar in at least three proteins in the alignment are boxed in yellow. Positions that are absolutely conserved are boxed in red. β, β-strand; T, turn