FIGURE 3.
Parasite killing is associated with a Th1 immune response. A, Cytokines and B, nitric oxide (NO) end-products measured in antigen-stimulated cultures of CLN cells collected from PHIL and C57BL/6 mice at 17 dpoi. C, Detection of iNOS in skeletal muscle (brown color), 17 dpoi. Arrowhead indicates larva and arrows indicate cellular infiltrates. Scale bar = 100 μm. D, Design of L-NIL treatment study. E, Effect of L-NIL treatment on NO-end products in cultures of CLN, 24 dpoi. F, Effect of L-NIL treatment on larval burdens 24 dpoi. Values represent means ± SD, n = 3 - 4 mice. *p <0.05, ** p < 0.001.
