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. Author manuscript; available in PMC: 2014 Nov 16.
Published in final edited form as: Dev Neurosci. 2013 Nov 16;35(6):474–490. doi: 10.1159/000355874

Figure 6.

Figure 6

Motor learning and rearing deficits were evident after frontal TBI. Mice were tested on the rotarod across three consecutive days (a). At adolescence, TBI mice showed a significant reduction in the mean latency to fall at days 2 and 3 (2-way RM ANOVA, post-hoc *p<0.05, ***p<0.001) compared to sham-operated mice. Although less pronounced, this injury-dependent impairment was also evident at adulthood (post-hoc, *p<0.05). Rearing behavior measured in the open field task was also used to detect forelimb motor function (b). While adolescent sham and TBI mice did not differ, adult TBI mice showed a significant deficit in rearing behavior compared to their respective shams, with a reduction in the time spent rearing (t1,17=3.560, p=0.0024; n=10/group).