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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Cell Host Microbe. 2014 Jan 15;15(1):47–57. doi: 10.1016/j.chom.2013.12.007

Figure 1. Widespread redundancies in B12 transport in human gut microbial genomes.

Figure 1

(A) Over 80% of sequenced human gut microbial species (260/313) encode B12-dependent genes or riboswitches. (B) Most of these 260 species lack the genes required to synthesize B12 de novo and rely on transport to meet their B12 requirements. Species that encode B12 transport are shown in orange and those that possess partial or complete B12 biosynthetic pathways are marked in green; species with both of these capabilities are designated with a hatched pattern. (C) The majority of human gut Bacteroidetes encode multiple B12 transporters within their genomes. See also Figure S1.