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Post-translational modification of progesterone receptors. Schematic of PR-A and PR-B showing the location of basal and hormone dependent (*) serine (S) phosphorylation sites; the Lys (K)388 SUMO conjugation site within an IKEE motif; and an acetylation consensus KxKK site (amino acids 638-641). Site(s) for ubiquitination remain unclear. BUS, B-upstream segment; DBD, DNA binding domain; LBD, ligand binding domain. Also shown are putative functions of some sites.
