Table 3.
Significant peptide peaks differentiating BTC from healthy volunteers
|
Mass (m/z) |
Peak area |
Peak area |
Fold- change |
Wilcoxon test |
AUROC
†
|
|---|---|---|---|---|---|
| BTC +/- SD | H +/- SD | (BTC vs H) | P value | ||
| 887.2 |
5.2+/-7.1 |
1.8+/-0.5 |
2.82 |
0.000691 |
0.79 |
| 1263.7 |
21.8+/-9.9 |
47.4+/-22.7 |
0.46 |
<0.000001 |
0.91 |
| 1350.8 |
48.3+/-25.7 |
117.4+/-62.3 |
0.41 |
<0.000001 |
0.92 |
| 2082.1 |
10.0+/-3.4 |
24.4+/-20.5 |
0.41 |
0.0000364 |
0.86 |
| 2210.3 |
10.9+/-3.8 |
38.2+/-31.6 |
0.29 |
<0.000001 |
0.92 |
| 2554.5 |
24.8+/-17.8 |
57.3+/-20.6 |
0.43 |
<0.000001 |
0.91 |
| 2903.3 |
24.1+/-10.0 |
11.5+/-2.5 |
2.09 |
<0.000001 |
0.97 |
| 5805.0 | 33.0+/-30.9 | 6.7+/-1.6 | 4.93 | <0.000001 | 0.96 |
*Wilcoxon test P values were corrected for multiple testing using the Benjamini-Hochberg adjustment. † Area under the Receiver Operating Characteristic curve.