Table 2.
Results of CNIT Analysis in European Americans
| Predictor | Hazard Ratio (95% CI) | P-value |
|---|---|---|
| Univariate Clinical Variable Model | ||
| Recipient Age per year | 1.05 (1.01–1.08) | 9.85 × 10−3 |
| Pre-transplant CKD | 3.69 (1.36–10.01) | 0.01 |
| Pre-Transplant eGFR per ml/min/1.73m2 | 0.96 (0.94–0.98) | 1.03 × 10−3 |
| Prior Diabetes Mellitus | 6.92(2.64–18.54) | 8.33 × 10−5 |
| Multivariable Genetic Model | ||
| DPYD rs1801265 | 0.45 (0.22–0.93) | 0.03 |
| UGT2B17 rs1902023 | 2.23 (1.21–4.11) | 0.01 |
| SLCO1B1 rs4149056 | 0.38(0.14–0.96) | 0.03 |
| SLC22A1 rs34305973 | 2.14(1.18–3.90) | 0.01 |