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CI-1033 selectively inhibits the proliferation of NF1 MPNST cell lines. On day 0, plates were treated with either vehicle or the indicated concentration of CI-1033. Cells were harvested and counted using the Trypan Blue exclusion assay. These data show the effects of CI-1033 on both total cell number (top panel) and percent viability (lower panel). Data are mean ± S.D. and are representative of three separate experiments for each line.
