Table 1.

Baseline characteristics of ALS cohort

Cohort (N)	Male/Female (N)(%) (N=342)	Age at Onset (y)(CI) (N=312)	Bulbar Site of Onset (N)(%) (N=313)	Duration (y)(CI) (N=312)	FH Motor Neuron Disease (N)(%)(N=313)	FH Neuro-degeneration (N)(%)(N=313)	Neuropathology (N)(%) (N=342)	TDP-43 Type (1/2/3)(%) (N=30)	Known Mutations (N)(%)
342	176/166 (51/49)	58.8 (57.6–60.0)	74/239 (24/76)	3.4 (3.1–3.8)	37/276 (12/88)	157/156 (50/50)	52/290 (15/85)	0/0/30 (0/0/100)	36 (11%)

Abbreviations: ALS = amyotrophic lateral sclerosis, N = number, y = years, CI = 95% confidence interval, and FH is family history. To estimate disease duration, intervals between age at onset and age at death or between age at onset and current age were calculated.