Table 2.
Baseline characteristics of FTLD-TDP and control cohorts
Method | Cohort | Number (N) | Male/Female (N)(%) | Age * (y)(CI) | Neuropathology (N)(%) | TDP-43 Type (1/2/3)(%) | Known Mutations (N)(%) |
---|---|---|---|---|---|---|---|
Sequencing | FTLD-TDP | 141 | 76/65 (54/46) | 73.1 (71.3–74.9) | 141/0 (100/0) | 77/23/28 (60/18/22) | 54 (38%) |
TaqMan | CON | 1167 | 536/631 (46/54) | 70.8 (70.2–71.5) | N/A | N/A | N/A |
Abbreviations: FTLD-TDP = frontotemporal lobar degeneration with TDP-43 pathology, CON = control subjects, and N/A = not applicable.
Age at death is shown for FTLD-TDP patients, and age at sampling for control subjects.