Figure 3.
Study design. Baseline urine collections to qualify for the study were collected on a free-choice diet. Patients were placed on a controlled metabolic diet on the first and last week of the study. Two time zero 24-h urine samples were collected on days 5 and 6 of the first week on the controlled metabolic diet (time zero urines) before study preparation was initiated. The probiotic or placebo was then administered for 4 weeks (weeks 2–5). Patients were next placed back on the controlled metabolic diet for the final week of the study (week 5), with two more final urine sample collections on days 5 and 6 of that week (final urines).