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. Author manuscript; available in PMC: 2014 Feb 13.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2013 Feb 4;86(1):136–142. doi: 10.1016/j.ijrobp.2012.12.007

Figure 5.

Figure 5

Probe activation and the tumor microenvironment. (A) Untreated mice or (B) mice treated with 5 Gy were injected with VM249 7 days after completion of RT. Tumors were harvested six hours after probe injection and unfixed tumor frozen sections were stained with the macrophage marker F4/80 and nuclear stain DAPI. (C) Sarcoma bearing Rosa26YFP/YFP; LSL-KrasG12D; p53Fl/Fl mice were injected with Prosense 680 and the tumor was removed 24 hours later. Cells from the tumor were stained for CD11b and sorted by flow cytometry (D).