Table 1.

Percent of chromosome errors in SAEC cells following treatment with MWCNT orV ₂ 0 ₅

Dose MWCNT μg/cm 2	Total % aneuploid cells	% loss of chromosome 1	% gain of chromosome 1	% loss of chromosome 4	% gain of chromosome 4	% gain of both chromosomes
Diluent	2.25 ± 1.0	1.0 ± 1.0%	1.0 ± 1.0%	1.25 ± 1.0%	1.0 ±1.0%	0
0.024	42 ±10*	2.0 ± 1.26	15.0 ± 2.0*	3.0 ± 1.26*	16.4 ± 2.0*	12.0 ± 3.0*
0.24	49 ±6.0	1.7 ± 0.7*	23.7 ± 5.0*	2.0 ± 10*	25 ± 4.0*	18 ± 6.0*
2.4	59.0 ± 6.0*	3.4 ± 0.8*	26.0 ± 3.0*	4.3 ± 1.2*	25 ± 10*	23 ± 5.0*
24	62 ±7.0*	7 ± 3.0%*	49.3 ± 4.0%*	8.0 ±3.0%*	53.3 ± 5%*	44 ± 5.0%*
Dose vanadium μg/cm2
0.31	69.0 ±7.0*	23.0 ± 5.0*	35.0 ± 9.0*	25.0 ± 11*	34.0 ± 7*	19.0 ± 6*

*Statistically significant at p < .05.

The distribution of the aneuploidy that was contributed by chromosome 1 and by chromosome 4 is detailed in the table as “Total % aneuploid cells”. The percent of cells with a gain in chromosome 1 and/or of chromosome 4 are indicated in the table under “Gain” of each chromosome. Cells with both chromosomes gained are indicated by “Gain of both chromosomes”. Cells with a loss of chromosome 1 and/or chromosome 4 are indicated in the table under “Loss” of each chromosome. *: p <0.05 of the treated cells compared to diluent control exposed cultures; ± standard deviation.