Table 2.

Incidence and frequency of symptoms

	WUs (n=204)		NAUs (n=160)		P-value
	%	n	%	n
Experienced heart palpitations
No	57a	117	31a	50	<0.0001
Yes	43a	87	69a	110
Experienced irregular heartbeat
No	41a	84	30a	48	0.028
Yes	59a	120	70a	112
Experienced lack of energy
No	27	54	21	33	0.194
Yes	74	150	79	127
Experienced dizziness
No	51a	104	34a	55	0.002
Yes	49a	100	66a	105
Experienced chest discomfort
No	72a	147	52a	83	<0.0001
Yes	28a	57	48a	77
Experienced shortness of breath
No	41	83	36	57	0.325
Yes	59	121	64	103
Overall frequency of indigestion
Not at all	78a	159	44a	70	<0.0001
Less than once a month	10a	21	21a	34
Between once a month and once a week	7a	15	18a	28
Between once a week and once a day	3a	5	14a	23
Once a day or more	2	4	3	5
Overall frequency of heartburn
Not at all	74a	151	45a	72
Less than once a month	14	29	16	26
Between once a month and once a week	6a	13	17a	27
Between once a week and once a day	4a	9	13a	20
Once a day or more	1a	2	9a	15
Overall frequency of regurgitation
Not at all	76a	155	56a	89	<0.0001
Less than once a month	18	36	21	33
Between once a month and once a week	4a	8	13a	21
Between once a week and once a day	2a	3	8a	13
Once a day or more	1	2	3	4
Overall frequency of nausea
Not at all	86a	176	54a	87	<0.0001
Less than once a month	7a	15	19a	30
Between once a month and once a week	3a	7	16a	26
Between once a week and once a day	2a	3	9a	14
Once a day or more	2	3	2	3
Overall frequency of stomach pain
Not at all	79a	162	49a	78	<0.0001
Less than once a month	12a	24	22a	35
Between once a month and once a week	6a	12	21a	33
Between once a week and once a day	0.5a	1	6a	10
Once a day or more	3	5	3	4

Note:

^aValues are significantly different at P<0.05 in the two-sided test of equality for column proportions and equality of means.

Abbreviations: WUs, warfarin users; NAUs, newer anticoagulant users.