. 2014 Feb 7;8:167–177. doi: 10.2147/PPA.S56187

Table 3.

Medication characteristics and adherence

	Warfarin users (n=204)		Dabigatran users (n=160)		P-value
	Mean	SD	Mean	SD	P-value
Doses missed	0.63	1.78	0.65	1.78	0.916
Doses taken less than the prescribed amount	0.23	1.36	0.19	0.62	0.784
	%	n	%	n

Frequency of medication use per day
Once	94^a	192	28^a	44	<0.0001
≥Twice	6^a	12	73^a	116
I wanted to avoid the side effects of the medication
No	100^a	33	98^a	42	0.378
Yes	0.0^a	0	2^a	1
I forgot to take my medication
No	24	8	33	14	0.428
Yes	76	25	67	29
I didn’t think my medication was working
No	100	33	100	43	N/A
I had a change in routine
No	94^a	31	65^a	28	0.003
Yes	6^a	2	35^a	15
I fell asleep
No	91	30	79	34	0.161
Yes	9	3	21	9
I was too busy
No	91	30	84	36	0.358
Yes	9	3	16	7
It was recommended by my physician
No	88^a	29	100^a	43	0.019
Yes	12^a	4	0^a	0
I had a difficult time paying for the medication
No	100	33	100	43	N/A
I ran out of medication
No	97	32	93	40	0.445
Yes	3	1	7	3
I was concerned about interactions with alcohol
No	97^a	32	100^a	43	0.251
Yes	3^a	1	0^a	0
I was already taking too many medications
No	100^a	33	98^a	42	0.378
Yes	0^a	0	2^a	1
I was concerned about the risk of bleeding due to an activity I was going to do
No	91^a	30	100^a	43	0.044
Yes	9^a	3	0^a	0
I was bothered by stomach-related (gastrointestinal) side effects
No	100^a	33	98^a	42	0.378
Yes	0^a	0	2^a	1
I was bothered by side effects that were not stomach-related
No	97^a	32	100^a	43	0.251
Yes	3^a	1	0^a	0
Other reasons for nonadherence
No	88	29	93	40	0.442
Yes	12	4	7	3

Note:

Values are significantly different at P<0.05 in the two-sided test of equality for column proportions and equality of means.

Abbreviations: N/A, not applicable; SD, standard deviation.