Table 1.
Characteristics of participants with all required data elements
| Total (N = 707) median [IQR] or n (%) | India/South America (n = 262) median [IQR] or n (%) | Africa* (n = 445) median [IQR] or n (%) | Africa TB-positive (n = 54) median [IQR] or n (%) | Africa TB-negative (n = 391) median [IQR] or n (%) | P value (within Africa) | |
|---|---|---|---|---|---|---|
| Age, years | 33 [28–40] | 34 [28–40] | 33 [28–39] | 34 [27–41] | 33 [28–39] | 0.35 |
| Male sex | 259 (37) | 129 (49) | 130 (29) | 19 (35) | 111 (28) | 0.34 |
| Country | ||||||
| Peru | 4 (1) | 4 (2) | ||||
| Malawi | 22 (3) | 22 (5) | 1 (2) | 21 (5) | ||
| Brazil | 27 (4) | 27 (10) | ||||
| South Africa | ||||||
| Soweto | 49 (7) | 49 (11) | 0 | 49 (13) | ||
| Johannesburg | 54 (8) | 54 (12) | 8 (15) | 46 (12) | ||
| University of KwaZulu-Natal, Durban | 77 (11) | 77 (17) | 17 (31) | 60 (15) | ||
| Center for the AIDS Programme of Research in South Africa, Durban | 134 (19) | 134 (30) | 17 (31) | 117 (30) | ||
| India | ||||||
| Byramjee Jeejeebhoy Medical College, Pune | 74 (11) | 74 (28) | ||||
| National AIDS Research Institute, Pune | 157 (22) | 157 (60) | ||||
| Botswana | 109 (15) | 109 (24) | 11 (20) | 98 (25) | ||
| Ethnic origin | ||||||
| Black African | 453 (64) | 9 (3) | 444 (100) | |||
| Asian | 232 (33) | 231 (88) | 1 (0) | |||
| White | 14 (2) | 14 (5) | 0 | |||
| Other | 8 (1) | 8 (3) | 0 | |||
| CD4+ cell count/mm3 | 272 [166–439] | 297 [190–454] | 259 [155–435] | 202 [88–334] | 271 [166–443] | 0.003 |
| BMI | 22.23 [19.60–26.30] | 20.93 [18.89–23.92] | 23.48 [20.14–27.99] | 21.10 [18.75–25.56] | 23.64 [20.42–28.14] | 0.004 |
| Karnofsky score | 90 [90–100] | 100 [90–100] | 90 [90–100] | 90 [80–90] | 90 [90–100] | <0.001 |
*
Zimbabwe site patients excluded due to laboratory problems with sputum samples (n = 5).
TB = tuberculosis; IQR = interquartile range; BMI = body mass index.