Table 1.

Patient, Tumor and Treatment Characteristics, Overall and by Radiation Modality

Factor	Overall (n=676)	3DCRT group (n=413, 61%)	IMRT group (n=263, 39%)	P-Value
Age at diagnosis	63.48 (10.67)	63.50 (10.33)	63.45 (11.20)	P=0.95
Gender
female	97 (14.3%)	56 (13.6%)	41 (15.6%)	P=0.47
male	579 (85.7%)	357 (86.4%)	222 (84.4%)
Overall Stage
1	11 (1.6%)	5 (1.2%)	6 (2.3%)	P=0.26
2	234 (34.6%)	149 (36.1%)	85 (32.3%)
3	379 (56.1%)	223 (54.0%)	156 (59.3%)
4a	52 (7.7%)	36 (8.7%)	16 (6.1%)
Lesion Location
Upper	56 (8.3%)	29 (7.0%)	27 (10.2%)	P=0.15
Middle	39 (5.8%)	23 (5.6%)	16 (6.1%)
Low	578 (85.5%)	359 (86.9%)	219 (83.3%)
Degree of tumor
Differentiation
Well differentiated	8 (1.2%)	5 (1.2%)	3 (1.1%)	P<0.01
Moderately	238 (35.2%)	129 (31.2%)	109 (41.5%)
Poorly	383 (56.7%)	233 (56.4%)	150 (57.0%)
Unknown	47 (6.9%)	46 (11.1%)	1 (0.4%)
Surgery
Yes	312 (46.2%)	197 (47.7%)	115 (43.7%)	P=0.31
No	364 (53.8%)	216 (52.3%)	148 (56.3%)
Induction Chemo
Yes	287 (42.5%)	193 (46.7%)	94 (35.7%)	P<0.01
No	389 (57.5%)	220 (53.3%)	169 (64.3%)
Performance Status
90–100	293 (43.3%)	205 (49.6%)	88 (33.5%)	P<0.01
80	298 (44.1%)	162 (39.2%)	136 (51.7%)
≤70	83 (12.3%)	44 (10.7%)	39 (14.8%)
Radiation Dose (median, range)	50.4 Gy (6.6–66)	50.4 Gy (6.6–66)	50.4 Gy (16.2–66)	P=0.84
Baseline PET (N, (%))	478 (70.7%)	226 (54.7%)	252 (95.8%)	P<0.01
FEV1 (L) (mean, (95%CI))*	3.12 (3.03, 3.21)	3.22 (3.09, 3.34)	3.04 (2.92, 3.17)	P=0.09
FEV1 (% pred) (mean, (95% CI)) *	93.1 (90.9, 95.3)	89.6 (86.4, 92.7)	95.9 (92.9, 98.9)	P<0.01
CHF (N, %)	13 (1.92)	9 (2.18)	4 (1.52)	P=0.53

^*Only 161 3DCRT and 204 IMRT pts had PFT values; CHF=Congestive Heart Failure