FIGURE 8:

Transport of membrane receptor SSTR3 is impaired after SSX2IP knockdown in RPE-1 cells. (a) Cells were transfected with control or SSX2IPs siRNA and stained for SSTR3 and glutamylated (glu) tubulin using indirect immunofluorescence. (b) Quantification of signal intensity of SSTR3 in the cilium. Left (bars), mean values of averages ± SEM from three independent experiments (n ≥ 150) normalized to controls. Right (box-and-whiskers plots), quantification of a single representative experiment. *p < 0.05, **p < 0.01, ***p < 0.001 (two-tailed Student's t test).