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. 2014 Feb 13;10(2):e1003470. doi: 10.1371/journal.pcbi.1003470

Figure 5. The effects of p.Arg154Trp and p.Gln142Leu mutations on the predicted structure of the MKK4-JNK3 complex.

Figure 5

A. The predicted structure of the wild-type MKK4-JNK3 complex with predicted binding energy of −12.66 energy units. B. The predicted structure of the mutant MKK4-JNK3 complex (Arg154Trp) with predicted binding energy of −12.84 energy units aligned with the wild-type complex. C. The predicted structure of the mutant MKK4-JNK3 complex (Gln142Leu) with predicted binding energy of −41.14 energy units aligned with the wild-type complex. Yellow/purple/green and pink balls: residue atoms on MKK4 and JNK3, respectively; red balls: mutated residue atoms.