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. 2014 Feb 13;10(2):e1003470. doi: 10.1371/journal.pcbi.1003470

Figure 6. SNPs/mutations mapped on the predicted complex of IL-1α with IL1R1.

Figure 6

IL1A (Interleukin 1 alpha) – IL1R1 (Interleukin 1 type I receptor) complex: Ile 68 (p.Ile68Asn SNP) is on the interface as a computational hot spot residue* and Ile276 (p.Ile276Thr mutation - endometrioid carcinoma) is a nearby residue for the interface. Orange and blue balls: residue atoms related to the SNP and the mutation on IL1A and IL1R1, respectively.