Table 2. The distribution of oncogenic mutations and SNPs on structures of interacting protein-protein complexes in IL-1 pathway.

Interacting Protein Pairs		COSMIC on Interface	COSMIC on Nearby	LS-SNP on Interface	LS-SNP on Nearby	Interacting Protein Pairs		COSMIC on Interface	COSMIC on Nearby	LS-SNP on Interface	LS-SNP on Nearby
1nfiE	1nfiA	0	0	1	1	1ukh	1fosF	3	3	0	0
2pph	1lb6	2	0	0	1	2o61	3hct	2	2	0	0
4h36A	4h36B	0	0	0	1	3o17	3alo	2	4	0	1
2yiy	2yiy	0	0	0	0	2dyl	3npc	3	3	0	1
3aln	3gc8	2	1	0	0	3brvB	1nfiE	0	0	2	2
1mod	1wgl	0	0	2	0	1oy3	1ikn	0	0	0	2
3mopC	3mopG	1	1	1	1	4hga	3kn6	0	2	1	1
1t2k	4fv7	0	0	0	0	1lb4	4g3d	3	0	2	0
3hcs	2j4o	1	4	3	1	2eva	2dyl	3	1	0	1
1nfiE	1nfiD	0	0	2	0	2hw6	3gc8	0	0	2	0
4depA	4depC	3	1	0	0	1wzy	1fos	2	2	1	0
4depB	4depC	1	0	0	3	2ac3	4fv0	0	1	0	1
2jrh	3fme	1	1	1	0	2mod	2z5v	2	1	0	0
3kn5	1tvo	2	2	1	0	3vut	3e7o	6	3	1	1
2y8oB	2y8oA	0	0	1	0	1ukh	1t2k	3	1	0	0
1s9i	4fv7	0	1	0	1	2y9qA	2y9qB	3	1	0	0
1svc	1oy3	0	0	1	0	3brtA	3brtB	0	0	3	2
1jnm	3npc	2	2	1	2	3vn9	3gp0	2	1	2	4
3mopK	3mopG	1	0	2	3	2zoq	1vzo	1	0	1	0
3hcs	3mopK	2	2	3	2	2pph	3vut	7	2	0	1
1dux	2baj	0	0	2	1	1w82	3aln	3	8	1	1
3elj	1dux	3	3	1	0	3fv8	2dyl	1	4	2	1
3tei	1nkp	1	5	0	0	3mopG	1lb5	0	5	1	1
1fosEG	1ukh	3	3	0	1	1nfiAC	3brtB	0	0	0	2
3gutB	1nfiB	0	0	0	0	2js7	1lb6	2	3	1	0
3gutB	3gutA	0	0	2	0	1t2k	3gp0	0	0	0	1
1t2k	3kn5	0	0	2	2	3aln	3fv8	2	3	1	0
2p55	4fv4	5	2	0	0	2eva	4dn5	3	5	0	1
1nfiAC	1oy3	0	0	3	1	2jbo	3gc9	2	0	1	2
3ody	2hw6	0	0	0	2	1fosE	1fosF	3	3	1	2
3mop	1wgl	3	1	0	3	3que	1t2k	0	0	2	1
1nfiB	1nfiA	0	0	2	0	2l5x	4depC	1	2	4	1
2jbo	3q9q	2	2	2	7	1mod	2z5v	3	1	0	0
3kn5	1kv1	3	1	3	1	3alo	2yiy	7	3	1	0
3gc9	1vzo	1	0	2	2	2eva	3vn9	3	4	0	1
1fosF	2r9s	0	1	0	0	2onlA	2onlC	3	1	2	3
2zdu	1fosE	1	1	1	0	4depA	4depB	3	5	5	6
2eva	2eci	1	3	0	0	2l5x	4depB	3	2	4	8
2c60	2dyl	4	2	1	1