Figure 4. The PWD chr19 reduces respiratory and bone abnormalities of Lamc2^jeb/jeb mice.

AB, Lung pressure-volume (PV) loop comparisons (A) and lung resistance and compliance measurements (B) from 7–9 male B6 wt, B6-Lamc2^jeb/jeb, B6.chr19^PWD wt and B6.chr19^PWD Lamc2^jeb/jeb mice at 18–19 wks of age. C, Total bone mineral density (BMD), total bone mineral content (BMC), percent fat, total tissue mass, and body length from the same mice. *, P≤0.05; **, ≤0.01; ***, ≤0.001; ****, ≤0.0001 comparing wt and Lamc2^jeb/jeb mice matched for chr19. Percent changes comparing wt and Lamc2^jeb/jeb mice are indicated.